Phospho-MAP4K4 (Ser629) Polyclonal Antibody, AbBy Fluor™ 350 Conjugated
Product Specifications
Background
MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) belongs to the serine/threonine protein kinase family and specifically activates MAPK8/JNK. It may play a role in the response to environmental stress and is thought to function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF alpha signaling pathway. It interacts with the SH3 domain of the adapter protein Nck. MAP4K4-dependent signaling inhibits PPARG responsive gene expression, adipogenesis, and insulin stimulated glucose transport.
Synonyms
MAP4K4phospho S629; Hepatocyte progenitor kinase like/germinal center kinase like kinase; HGK; HPK/GCK like kinase; HPK/GCK like kinase HGK; KIAA0687; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; MEKKK4; Mitogen activated protein kinase kinase kinase kinase 4; Nck interacting kinase; NIK.
Gene ID
9448
Modification Site
Ser629
Cellular Locus
Cytoplasm
Host
Rabbit
Target
Phospho-MAP4K4 (Ser629)
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 350
Source
KLH conjugated synthetic phosphopeptide derived from human MAP4K4 around the phosphorylation site of Ser629
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
346nm/442nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
9448
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Horse, Chicken, Rabbit
More Discoveries
Explore Other Products
Browse additional items from our catalog
4042931 1 Each
Microscope slide individual Lilium Embryo sac : L.S seed
Sign In for Pricing
View Details 
MBS9022014-01 0.02 mg (E-Coli)
Recombinant Mouse Tripartite motif-containing protein 72 (Trim72)
Sign In for Pricing
View Details MBS9022014-02 0.1 mg (E-Coli)
Recombinant Mouse Tripartite motif-containing protein 72 (Trim72)
Sign In for Pricing
View Details