Phospho-MAP4K4 (Ser629) Polyclonal Antibody, APC Conjugated
Product Specifications
Background
MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) belongs to the serine/threonine protein kinase family and specifically activates MAPK8/JNK. It may play a role in the response to environmental stress and is thought to function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF alpha signaling pathway. It interacts with the SH3 domain of the adapter protein Nck. MAP4K4-dependent signaling inhibits PPARG responsive gene expression, adipogenesis, and insulin stimulated glucose transport.
Synonyms
MAP4K4phospho S629; Hepatocyte progenitor kinase like/germinal center kinase like kinase; HGK; HPK/GCK like kinase; HPK/GCK like kinase HGK; KIAA0687; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; MEKKK4; Mitogen activated protein kinase kinase kinase kinase 4; Nck interacting kinase; NIK.
Gene ID
9448
Modification Site
Ser629
Cellular Locus
Cytoplasm
Host
Rabbit
Target
Phospho-MAP4K4 (Ser629)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic phosphopeptide derived from human MAP4K4 around the phosphorylation site of Ser629
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
9448
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Horse, Chicken, Rabbit
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
KN400499 1 Kit
Complement factor B (CFB) Human Gene Knockout Kit (CRISPR)
Sign In for Pricing
View Details 
PDMH100066-01 20 µg
Recombinant Human Sortilin/SORT1 protein (His tag)
Sign In for Pricing
View Details PDMH100066-02 100 µg
Recombinant Human Sortilin/SORT1 protein (His tag)
Sign In for Pricing
View Details PDMH100066-03 500 µg
Recombinant Human Sortilin/SORT1 protein (His tag)
Sign In for Pricing
View Details PDMH100066-04 1 mg
Recombinant Human Sortilin/SORT1 protein (His tag)
Sign In for Pricing
View Details 