Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Phospho-MBP (Thr232) Polyclonal Antibody, APC-Cy7 Conjugated

Product Specifications

Background

The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.

Synonyms

Myelin basic protein; MBP; Myelin A1 protein; Myelin membrane encephalitogenic protein

Gene ID

4155

Swiss Prot

P02686

Modification Site

Thr232

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Phospho-MBP (Thr232)

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic phosphopeptide derived from human MBP around the phosphorylation site of Thr232

Applications

FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

1µg/µl

Dilution

FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-5474R-APC-Cy7

Specificity

This antibody recognizes Thr229 in mice and Thr122 in rat

Gene ID URL

4155

Predicted Cross Reactivity

Dog, Cow, Pig, Horse, Chicken, Rabbit

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

ZNF7 Antibody
A41516-50UG 50 µg

ZNF7 Antibody

Ask
View Details
MMP16, CT (MMP16, MMPX2, Matrix metalloproteinase-16, MMP-X2, Membrane-type matrix metalloproteinase 3, Membrane-type-3 matrix metalloproteinase) (Biotin)
MBS6321374-01 0.2 mL

MMP16, CT (MMP16, MMPX2, Matrix metalloproteinase-16, MMP-X2, Membrane-type matrix metalloproteinase 3, Membrane-type-3 matrix metalloproteinase) (Biotin)

Ask
View Details
MMP16, CT (MMP16, MMPX2, Matrix metalloproteinase-16, MMP-X2, Membrane-type matrix metalloproteinase 3, Membrane-type-3 matrix metalloproteinase) (Biotin)
MBS6321374-02 5x 0.2 mL

MMP16, CT (MMP16, MMPX2, Matrix metalloproteinase-16, MMP-X2, Membrane-type matrix metalloproteinase 3, Membrane-type-3 matrix metalloproteinase) (Biotin)

Ask
View Details
Gastrin Releasing Peptide (GRP) Rabbit pAb
A6380-01 20 µL

Gastrin Releasing Peptide (GRP) Rabbit pAb

Ask
View Details
Gastrin Releasing Peptide (GRP) Rabbit pAb
A6380-02 100 μL

Gastrin Releasing Peptide (GRP) Rabbit pAb

Ask
View Details
Gastrin Releasing Peptide (GRP) Rabbit pAb
A6380-03 500 μL

Gastrin Releasing Peptide (GRP) Rabbit pAb

Ask
View Details