Phospho-gamma Catenin (Tyr550) Polyclonal Antibody
Product Specifications
Background
Gamma Catenin is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of gamma Catenin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. It is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
Synonyms
Gamma Catenin phospho Y550; p-gamma Catenin phospho Y550; catenin cadherin-associated protein gamma 80kD; Catenin gamma; CTNNG; Desmoplakin 3; Desmoplakin III; Desmoplakin3; DesmoplakinIII; DP 3; DP III; DP3; DPIII; gamma catenin; Junction plakoglobin; JUP; PDGB; PKGB; PLAKOGLOBIN.
Gene ID
3728
Modification Site
Tyr550
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Target
Phospho-gamma Catenin (Tyr550)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic phosphopeptide derived from human JUP around the phosphorylation site of Tyr550
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
3728
Predicted Cross Reactivity
Human, Mouse, Rat
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