Phospho-gamma Catenin (Tyr550) Polyclonal Antibody

Product Specifications

Background

Gamma Catenin is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of gamma Catenin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. It is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.

Synonyms

Gamma Catenin phospho Y550; p-gamma Catenin phospho Y550; catenin cadherin-associated protein gamma 80kD; Catenin gamma; CTNNG; Desmoplakin 3; Desmoplakin III; Desmoplakin3; DesmoplakinIII; DP 3; DP III; DP3; DPIII; gamma catenin; Junction plakoglobin; JUP; PDGB; PKGB; PLAKOGLOBIN.

Gene ID

3728

Modification Site

Tyr550

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Target

Phospho-gamma Catenin (Tyr550)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic phosphopeptide derived from human JUP around the phosphorylation site of Tyr550

Applications

ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

3728

Predicted Cross Reactivity

Human, Mouse, Rat

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