Phospho-IFNAR1 (Ser535+Ser539) Polyclonal Antibody, PE-Cy5 Conjugated

Product Specifications

Background

Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. Can also transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.

Synonyms

AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC; Interferon alpha/beta receptor 1; IFN-R-1; IFN-alpha/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1; IFNAR1

Gene ID

3454

Swiss Prot

P17181

Modification Site

Ser535+Ser538

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat

Target

Phospho-IFNAR1 (Ser535+Ser539)

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy5

Source

KLH conjugated synthetic phosphopeptide derived from human IFNAR1 around the phosphorylation site of Ser535+Ser538

Applications

FCM

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

1µg/µl

Dilution

FCM (1:20-100)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3454

Predicted Cross Reactivity

Mouse, Dog, Cow, Sheep, Pig, Horse, GuineaPig

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