Phospho-IFNAR1 (Ser535+Ser539) Polyclonal Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. Can also transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
Synonyms
AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC; Interferon alpha/beta receptor 1; IFN-R-1; IFN-alpha/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1; IFNAR1
Gene ID
3454
Swiss Prot
P17181
Modification Site
Ser535+Ser538
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Rat
Target
Phospho-IFNAR1 (Ser535+Ser539)
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthetic phosphopeptide derived from human IFNAR1 around the phosphorylation site of Ser535+Ser538
Applications
FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
1µg/µl
Dilution
FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3454
Predicted Cross Reactivity
Mouse, Dog, Cow, Sheep, Pig, Horse, GuineaPig
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
123922-ML490 100 µL
BGN (Biglycan, Bone/Cartilage Proteoglycan I, PG-S1, SLRR1A) (MaxLight 490)
Ask
View Details 
168360 100 µg
MIP-1A (Macrophage Inflammatory Protein-1-alpha, Ccl3 cytokine, C-C motif chemokine 3, Small-inducible cytokine A3, Macrophage inflammatory protein 1-a, MIP-1-alpha, TY-5, SIS-alpha, Heparin-binding chemotaxis protein, L2G25B, Scya3 protein)
Ask
View Details 