Phospho-IGF1R (Tyr1165 + Tyr1166) Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008].
Synonyms
IGF-1R Tyr1165/Tyr1166; IGF1R phospho Y1165+Y1166; IGF1R phospho Tyr1165+Tyr1166; p-IGF1R Tyr1165+Tyr1166; CD221; CD221 antigen; IGF 1 receptor; IGF 1R; IGF I receptor; IGF1R; IGFIR; IGFIRC; Insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; JTK13; MGC142170; MGC142172; IGF1 Receptor; IGF1R_HUMAN.
Gene ID
3480
Swiss Prot
P08069
Modification Site
Tyr1165 + Tyr1166
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Mouse, Rat
Target
Phospho-IGF1R (Tyr1165 + Tyr1166)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic phosphopeptide derived from human IGF1R around the phosphorylation site of Tyr1165+Tyr1166
Applications
FCM
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
FCM (1:20-100)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3480
Predicted Cross Reactivity
Human, Dog, Cow, Pig, Chicken
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