Phospho-ILK-1 (Thr173) Polyclonal Antibody, APC-Cy5.5 Conjugated

Product Specifications

Background

Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.

Synonyms

P59; ILK-1; ILK-2; p59ILK; HEL-S-28; Integrin-linked protein kinase; 59 kDa serine/threonine-protein kinase; ILK; ILK1; ILK2

Gene ID

3611

Swiss Prot

Q13418

Modification Site

Thr173

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat

Target

Phospho-ILK-1 (Thr173)

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy5.5

Source

KLH conjugated synthetic phosphopeptide derived from human ILK-1 around the phosphorylation site of Thr173

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/694nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3611

Predicted Cross Reactivity

Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

E056230 1 Each

Mouse IGFBP-1 ELISA Kit

Ask

View Details

HY-W012537-01 1 mg

(2S,4R) -2-amino-4-hydroxypentanedioic acid

Ask

View Details

HY-W012537-02 5 mg

(2S,4R) -2-amino-4-hydroxypentanedioic acid

Ask

View Details

YF-PA19267 50 ug

anti-FAM3B

Ask

View Details

038211-ML750 100 µL

MAS1, CT (MAS1, MAS, Proto-oncogene Mas) (MaxLight 750) discontinued

Ask

View Details

FAB4681E 0.1 mL

Rat Monoclonal gp130/CD130 Antibody (125623) [DyLight 405]

Ask

View Details