HSP-60 Polyclonal Antibody

Heat shock proteins (HSPs) are a family of highly conserved stress response proteins. Heat shock proteins function primarily as molecular chaperones by facilitating the folding of other cellular proteins, preventing protein aggregation or targeting improperly folded proteins to specific degradative pathways. HSPs are typically expressed at low levels under normal physiological conditions but are dramatically upregulated in response to cellular stress. Heat Shock Protein 60 (HSP60), also known as Chaperonin 60 (CPN60), is a mitochondrial matrix protein belonging to a highly conserved family of molecular chaperone and stress response proteins. HSP60 plays a role in stabilizing and refolding proteins in response to heat-shock or other cellular stress. Full length human HSP60 is 98% identical to mouse and rat HSP60.

60 kDa heat shock protein;60-KD; CH60; fa04a05; heat shock 60kDa protein 1 (chaperonin) ; Heat shock protein 1 (chaperonin) ; Heat shock protein 60; Heat shock protein 65; heat shock protein family D (Hsp60) member 1; Hsp 60; HSP 65; mitochondrial; Mitochondrial matrix protein P1; P60 lymphocyte protein; short heat shock protein 60 Hsp60s1; HLD; SPG; CPN; Chaperonin; HSPD; HuCHA; GROEL; HLD4; HSP-60; HSP65; HuCHA60; SPG13; CPN60; Mitochond;60 kDa chaperonin; Chaperonin 60; HSP60; HSPD1