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Phospho-HDAC2 (Ser394) Polyclonal Antibody, HRP Conjugated

Product Specifications

Background

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4) . This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010].

Synonyms

HDAC2 Ser394; HDAC2 phospho S394; HDAC2 phospho Ser394; p-HDAC2 Ser394; histone deacetylase 2; D10Wsu179e; EC 3.5.1.98; HD2; HDAC 2; Hdac2; histone deacetylase 2; RPD3; transcriptional regulator homolog RPD3; YAF1; YY1 associated factor 1; YY1 transcription factor binding protein; Yy1bp; HDAC2_HUMAN.

Gene ID

3066

Modification Site

Ser394

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

Phospho-HDAC2 (Ser394)

Clonality

Polyclonal

Isotype

IgG

Conjugation

HRP

Source

KLH conjugated synthetic phosphopeptide derived from human HDAC2 around the phosphorylation site of Ser394

Applications

WB, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3066

Predicted Cross Reactivity

Rat, Dog, Cow, Pig, Horse, Chicken

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