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Phospho-HMG14 (Ser20+Ser24) Polyclonal Antibody, PE-Cy5 Conjugated

Product Specifications

Background

Chromosomal protein HMG14 binds to the inner side of the nucleosomal DNA, thus altering the interaction between the DNA and the histone octamer and is involved in the process that maintains transcribable genes in an appropriate chromatin conformation. HMG14 has been implicated as a contributing factor in the etiology of Down syndrome.

Synonyms

HMG14 phospho S21 + S25; High mobility group nonhistone chromosomal protein 14; High mobility group nucleosome binding 1; High mobility group nucleosome binding domain containing protein 1; High mobility group protein 14; High-mobility group nucleosome binding domain 1; HMG14; HMGN 1; HMGN1; MGC104230; MGC117425; Nonhistone chromosomal protein HMG-14; Nonhistone chromosomal protein HMG14; FLJ27265; FLJ31471.

Gene ID

3150

Modification Site

Ser21+Ser25

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Target

Phospho-HMG14 (Ser20+Ser24)

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy5

Source

KLH conjugated synthetic phosphopeptide derived from human HMGN1 around the phosphorylation site of Ser20+Ser24

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3150

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Pig, Chicken, Rabbit

Curated Selection

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