Phospho-GABBR1 (Ser923) Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA (A/C) ] receptors, to produce fast synaptic inhibition, and metabotropic [GABA (B) ] receptors, to produce slow, prolonged inhibitory signals. The GABA (B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA (B) receptor 1 and GABA (B) receptor 2. The GABA (B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jun 2009].
Synonyms
GABBR1 phospho S1180; GABBR1 phospho Ser1180; p-GABBR1 Ser1180; GABAb Receptor 1; dJ271M21.1.1; dJ271M21.1.2; FLJ92613; GAB B R1; GABA B R1; GABAB R1; GABAB subunit 1c; GABAB1e; GABABR 1; GABABR1; GABB R1; GABBR 1; GABBR1 3; GABBR1; Gamma aminobutyric acid GABA B receptor 1; Gamma aminobutyric acid B receptor 1; Gamma aminobutyric acid type B receptor subunit 1; Gb 1; Gb1; GPRC 3A; GPRC3A; hGB1a; GABR1_HUMAN; Gamma-aminobutyric acid type B receptor subunit 1; GABA B Receptor 1; GABA-B receptor 1; GABA-B-R1; GABA-BR1; GABABR1; Gb1; Seven transmembrane helix receptor.
Gene ID
54393
Modification Site
Ser923
Cellular Locus
Secreted, Cell membrane
Host
Rabbit
Target
Phospho-GABBR1 (Ser923)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic phosphopeptide derived from mouse GABBR1 around the phosphorylation site of Ser923
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
54393
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit, GuineaPig
More Discoveries
Explore Other Products
Browse additional items from our catalog