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Phospho-FANCG (Ser383) Polyclonal Antibody, FITC Conjugated

Product Specifications

Background

FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies. A minimum of 8 FA genes have been identified.

Synonyms

FANCG phospho S383; p-FANCG phospho S383; DNA repair protein XRCC9; DNA-repair protein XRCC9; FAG; Fanconi anaemia complementation group G; Protein FACG; X ray repair, complementing defective, in Chinese hamster cells 9; XRCC9.

Gene ID

2189

Modification Site

Ser383

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Target

Phospho-FANCG (Ser383)

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic phosphopeptide derived from human FANCG around the phosphorylation site of Ser383

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2189

Predicted Cross Reactivity

Human, Mouse, Rat

Curated Selection

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