E3 ligase Ligand 18
E3 ligase Ligand 18 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 18 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
Product Specifications
CAS Number
[2241669-88-3]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-18-1.html
Purity
99.22
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
CC(N[C@H](C(O)=O)CSC1=NC(C(N=C(N)N2)=O)=C2N1CC3=CC=C(Cl)C=C3)=O
Molecular Formula
C17H17ClN6O4S
Molecular Weight
436.87
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Heterocyclic compound. WO2018143403A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Recombinant Yersinia pestis UPF0299 membrane protein YPDSF_1460 (YPDSF_1460), partial
![Rabbit Monoclonal CD99 Antibody (MIC2/3478R) [HRP]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
JAK3 (Janus Kinase 3, EC 2.7.10.2, JAKL, Leukocyte Janus Kinase, LJAK) (AP) discontinued