Phospho-EIF4EBP1 (Ser111) Polyclonal Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Synonyms
Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I; EIF4EBP1
Gene ID
1978
Modification Site
Ser112
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
Phospho-EIF4EBP1 (Ser111)
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthetic phosphopeptide derived from mouse 4EBP1 around the phosphorylation site of Ser112
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1978
Predicted Cross Reactivity
Rat, Dog, Cow, Horse
More Discoveries
Explore Other Products
Browse additional items from our catalog
K4218602 1.0 µg DNA
Olfr353 sgRNA CRISPR Lentivector (Mouse) (Target 1)
Sign In for Pricing
View Details 
E33F100486 10 µg
Human TAAR9 full length protein-synthetic nanodisc
Sign In for Pricing
View Details LV785873 1.0 µg DNA
SLC9A3P4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 246739 50 µL
GPS1 (G Protein pathway Suppressor 1, COPS1, CSN1, MGC71287)
Sign In for Pricing
View Details