H2Apan Polyclonal Antibody
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene ID
92815
Swiss Prot
Q7L7L0
Host
Rabbit
Cross Reactivity
Human
Target
H2A pan
Clonality
Polyclonal
Conjugation
Unconjugated
Source
Polyclonal antibody raised in rabbit against histone H2A using 2 KLH-conjugated synthetic peptides containing a sequence from the central and the C-terminal part of the protein
Applications
WB, ELISA, IF (ICC)
Purification
Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
Concentration
4µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
92815
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