BMI1 Polyclonal Antibody
Product Specifications
Background
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Synonyms
PCGF4, RNF51, FLVI2
Gene ID
648
Swiss Prot
P35226
Host
Rabbit
Cross Reactivity
Mouse
Target
BMI1
Clonality
Polyclonal
Conjugation
Unconjugated
Source
Polyclonal antibody raised in rabbit against mouse BMI1 using two KLH-conjugated synthetic peptides containing a sequence from the central and the C-terminal region of the protein, respectively
Applications
WB, ELISA
Purification
Whole antiserum from rabbit containing 0.05% azide
Concentration
Not Determined
Dilution
WB (1:300-5000), ELISA (1:500-1000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
648
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