CBX2 Polyclonal Antibody
Product Specifications
Background
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression.
Synonyms
Chromobox protein homolog 2, CBX2
Gene ID
84733
Swiss Prot
Q14781
Host
Rabbit
Cross Reactivity
Mouse
Target
CBX2
Clonality
Polyclonal
Conjugation
Unconjugated
Source
Polyclonal antibody raised in rabbit against mouse CBX2 (chromobox homolog 2) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein
Applications
ELISA
Purification
Whole antiserum from rabbit containing 0.05% azide
Concentration
Not Determined
Dilution
ELISA (1:500-1000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
84733
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