ZBTB4 Polyclonal Antibody

Product Specifications

Background

Transcriptional repressor with bimodal DNA-binding specificity. Represses transcription in a methyl-CpG-dependent manner. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS) . Can also bind specifically to a single methyl-CpG pair and can bind hemimethylated DNA but with a lower affinity compared to methylated DNA (PubMed:16354688) . Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal.

Synonyms

Zinc finger and BTB domain-containing protein 4, ZBTB4

Gene ID

57659

Swiss Prot

Q9P1Z0

Host

Rabbit

Cross Reactivity

Human

Target

ZBTB4

Clonality

Polyclonal

Conjugation

Unconjugated

Source

Polyclonal antibody raised in rabbit against human ZBTB4 (zinc finger and BTB domain containing 4), using four different KLH-conjugated synthetic peptides