PAPD5 Polyclonal Antibody

Product Specifications

Background

Catalytic subunit of a TRAMP-like complex which has a poly (A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo (A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity (in vitro) . Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.

Synonyms

Non-canonical poly (A) RNA polymerase PAPD5, PAPD5, TRF4-2, TUTase 3, PAP-associated domain-containing protein 5

Gene ID

64282

Swiss Prot

Q8NDF8

Host

Rabbit

Cross Reactivity

Human

Target

PAPD5

Clonality

Polyclonal

Conjugation

Unconjugated

Source

Polyclonal antibody raised in rabbit against human PAPD5 (PAP associated domain containing 5), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of the protein