Phospho-Dnmt1 (Tyr399) Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
DNA (cytosine-5-) -methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
Synonyms
Dnmt1phospho Y399; Dnmt1 phospho Tyr399; p-Dnmt1 Tyr399; AIM; CXXC finger protein 9; CXXC-type zinc finger protein 9; CXXC9; DNA cytosine 5 methyltransferase 1; DNA cytosine-5-methyltransferase 1; DNA methyltransferase 1; DNA methyltransferase HsaI; DNA methyltransferase M.HsaI.; DNA MTase; DNA MTase HsaI; DNMT 1; DNMT; Dnmt1; Dnmt1; DNMT1_HUMAN; Dnmt1o; FLJ16293; HSN1E; M.HsaI; MCMT; Met1; MGC104992; mMmul; MommeD2.
Gene ID
1786
Modification Site
Tyr399
Cellular Locus
Nucleus
Host
Rabbit
Target
Phospho-Dnmt1 (Tyr399)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic phosphopeptide derived from human Dnmt1 around the phosphorylation site of Tyr399
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1786
Predicted Cross Reactivity
Human, Dog, Pig, Horse
Curated Selection
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