Phospho-Dnmt1 (Ser154) Polyclonal Antibody

Product Specifications

Background

DNA (cytosine-5-) -methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].

Synonyms

Dnmt1phospho S154; Dnmt1 phospho Ser154; p-Dnmt1 Ser154; AIM; CXXC finger protein 9; CXXC-type zinc finger protein 9; CXXC9; DNA cytosine 5 methyltransferase 1; DNA cytosine-5-methyltransferase 1; DNA methyltransferase 1; DNA methyltransferase HsaI; DNA methyltransferase M.HsaI.; DNA MTase; DNA MTase HsaI; DNMT 1; DNMT; Dnmt1; Dnmt1; DNMT1_HUMAN; Dnmt1o; FLJ16293; HSN1E; M.HsaI; MCMT; Met1; MGC104992; mMmul; MommeD2.

Gene ID

1786

Modification Site

Ser154

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

Phospho-Dnmt1 (Ser154)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic phosphopeptide derived from human Dnmt1 around the phosphorylation site of Ser153

Applications

ELISA, FCM, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC), IP

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200), IP (1-2ug)