MRG15 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.
Synonyms
Eaf3; MORF4L1; MORFRG15; Mortality factor 4 like 1; Mortality factor 4 like protein 1; MO4L1_HUMAN.
Gene ID
10933
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Mouse, Sheep
Immunogen
21-120/362
Target
MRG15
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human MRG15
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
10933
Predicted Cross Reactivity
Human, Rat, Dog, Cow, Pig, Horse, Rabbit
Curated Selection
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