Phospho-Caspase-9 (Ser196) Polyclonal Antibody, Cy3 Conjugated
Product Specifications
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) . Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Synonyms
MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP9
Gene ID
842
Swiss Prot
P55211
Modification Site
Ser196
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Phospho-Caspase-9 (Ser196)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy3
Source
KLH conjugated synthetic phosphopeptide derived from human CASP9 around the phosphorylation site of Ser196
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
512,550nm/570,615nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
842
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7036547-01 0.02 mg
Recombinant Avian infectious bronchitis virus Membrane protein (M)
Ask
View Details 
MBS7036547-02 0.1 mg
Recombinant Avian infectious bronchitis virus Membrane protein (M)
Ask
View Details MBS7036547-03 5x 0.1 mg
Recombinant Avian infectious bronchitis virus Membrane protein (M)
Ask
View Details 
