Phospho-Caspase 6 (Ser257) Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Caspase-6 is involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly (ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. Subunit is compose of heterodimer of a18 kDa (p18) and a 11 kDa (p11) subunit. Subcellular location at cytoplasmic. Cleavages by CPP32, caspase-8 or -10 generate the two active subunits. It belongs to the peptidase C14 family.
Synonyms
Apoptosis-related cysteine protein; Apoptosis Related Cysteine Protease; Apoptotic cysteine protease MCH2; Apoptotic protease MCH 2; Apoptotic protease MCH2; Casp 6; Casp6; Caspase 6 apoptosis related cysteine protease; Caspase 6 precursor; Caspase6; Human cysteine protease Mch2 isoform alpha; Mch 2; Mch2; CASP6_HUMAN.
Gene ID
839
Modification Site
Ser257
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Mouse
Target
Phospho-Caspase 6 (Ser257)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic phosphopeptide derived from human Caspase 6 around the phosphorylation site of Ser257
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
839
Predicted Cross Reactivity
Human, Rat
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![NANP Mouse Monoclonal Antibody [Clone ID: OTI2D11]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
MBS6141878-01 0.1 mL
FBXW7 (F-box and WD-40 Domain Protein 7, F-box and WD-40 Domain-containing Protein 7, F-box Protein FBW7, F-box/WD Repeat Protein 7, FBW7, Archipelago Drosophila Homolog of, Archipelago Homolog, AGO, CDC4, DKFZp686F23254, F-box Protein FBX30, FBX30, FBXO3
Ask
View Details 
MBS6141878-02 5x 0.1 mL
FBXW7 (F-box and WD-40 Domain Protein 7, F-box and WD-40 Domain-containing Protein 7, F-box Protein FBW7, F-box/WD Repeat Protein 7, FBW7, Archipelago Drosophila Homolog of, Archipelago Homolog, AGO, CDC4, DKFZp686F23254, F-box Protein FBX30, FBX30, FBXO3
Ask
View Details 