Phospho-ATG4D (Ser467) Polyclonal Antibody, Cy3 Conjugated
Product Specifications
Background
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. [provided by RefSeq].
Synonyms
APG4 D; APG4D; ATG4 autophagy related 4 homolog D; Atg4dl; AUT like 4 cysteine endopeptidase; AUTL4; Autophagin 4; Autophagy related cysteine endopeptidase 4; Autophagy related protein 4 homolog D; Cysteine protease ATG4D.
Gene ID
84971
Modification Site
Ser467
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Mouse
Target
Phospho-ATG4D (Ser467)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy3
Source
KLH conjugated syntheticphosphopeptide derived from human ATG4D around the phosphorylation site of Ser467 [RP (p-S) SE]
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
512,550nm/570,615nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
84971
Predicted Cross Reactivity
Human, Rat, Dog, Cow, Pig, Horse, Rabbit
Curated Selection
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