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Phospho-APC1 (Ser377) Polyclonal Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011].

Synonyms

Apc1 phospho S377; p-Apc1 phospho S377; ANAPC1Ser377; ANAPC 1; ANAPC1; Anaphase promoting complex subunit 1; anaphase-promoting complex 1 meiotic checkpoint regulator; Anaphase-promoting complex subunit 1; Apc 1; APC1; APC1_HUMAN; Cyclosome subunit 1; MCPR; Meiotic checkpoint regulator; Mitotic checkpoint regulator; Protein Tsg 24; Protein Tsg24; Testis-specic gene 24 protein; TSG 24; TSG24.

Gene ID

64682

Modification Site

Ser377

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Rat

Target

Phospho-APC1 (Ser377)

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic phosphopeptide derived from human ANAPC1 around the phosphorylation site of Ser377

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

64682

Predicted Cross Reactivity

Human, Mouse, Dog, Cow, Sheep, Pig, Horse, Rabbit

Curated Selection

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