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Thalidomide-piperazine (hydrochloride)

Thalidomide-piperazine hydrochloride has the potential for the research of leprosy and multiple myeloma. Thalidomide-piperazine hydrochloride used as a tool in developmental biology leads to important discoveries in the biochemical pathways of limb development[1].

Product Specifications

CAS Number

[2228029-82-9]

UNSPSC

12352005

Hazard Statement

H360

Target

Apoptosis; Autophagy; Ligands for E3 Ligase; Molecular Glues

Type

Reference compound

Related Pathways

Apoptosis; Autophagy; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/thalidomide-piperazine-hydrochloride.html

Purity

98.27

Solubility

H2O : 33.33 mg/mL (ultrasonic)

Smiles

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(N4CCNCC4)=C3)=O.[H]Cl

Molecular Formula

C17H19ClN4O4

Molecular Weight

378.81

Precautions

H360

References & Citations

[1]Kim JH, et al. Thalidomide: the tragedy of birth defects and the effective treatment of disease [published correction appears in Toxicol Sci. 2012 Feb;125 (2) :613]. Toxicol Sci. 2011;122 (1) :1-6.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Available Sizes

Curated Selection

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