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ProBNP Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.

Synonyms

BNP 32; BNP1-28; BNP1-29; BNP1-30; BNP1-32; BNP2-31; BNP3-29; BNP3-30; BNP3-32; BNP4-27; BNP4-29; BNP4-30; BNP4-31; BNP4-32; BNP5-29; BNP5-31; BNP5-32; Brain natriuretic peptide 32; Brain type natriuretic peptide; Gamma brain natriuretic peptide; Natriuretic peptide B; Natriuretic peptide brain type; Natriuretic peptide precursor B; natriuretic peptide, brain type; ANFB_MOUSE; Natriuretic peptides B; natriuretic protein; NPPB; NPPB protein.

Gene ID

18158

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

21-121/121

Target

ProBNP

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from mouse proBNP

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

18158

Curated Selection

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