Cytochrome b5 Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Synonyms
CYB 5; CYB 5A; CYB5; CYB5_HUMAN; CYB5A; Cytochrome b 5; Cytochrome b5 microsomal; Cytochrome b5; Cytochrome b5 type A microsomal; Cytochrome b5 type A; MCB 5; MCB5; Microsomal cytochrome b5; Microsomal cytochrome b5 type A; Type 1 cyt b5; CYB5A.
Gene ID
1528
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
9-80/134
Target
Cytochrome b5
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human Cytochrome b5
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1528
Predicted Cross Reactivity
Human, Dog, Cow, Sheep, Pig
Curated Selection
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