H3R17me2 (asym) K18ac Polyclonal Antibody
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene ID
8350
Swiss Prot
P68431
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
H3R17me2 (asym) K18ac
Clonality
Polyclonal
Conjugation
Unconjugated
Source
Polyclonal antibody raised in rabbit against the region of histone H3 containing the asymmetrically dimethylated R17 and the acetylated lysine 18, using a KLH-conjugated synthetic peptide.
Applications
WB, ELISA, IF, dot-blot
Purification
Purified by Protein A.
Concentration
0.95µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IF (), dot-blot ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
8350
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