H4K20me3 Polyclonal Antibody- Classic

Product Specifications

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene ID

121504

Swiss Prot

P62805

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

H4K20me3

Clonality

Polyclonal

Conjugation

Unconjugated

Source

Polyclonal antibody raised in rabbit against the region of histone H4 containing the trimethylated lysine 20 (H4K20me3), using a KLH-conjugated synthetic peptide

Applications

WB, ELISA, IF, dot-blot

Purification

Purified by Protein A.

Concentration

1.75µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IF (), dot-blot ()

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

121504

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