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MeCP2 Polyclonal Antibody

Product Specifications

Background

Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) -containing DNA, with a preference for 5-methylcytosine (5mC) .

Synonyms

Methyl-CpG-binding protein 2, MECP2, MeCp-2 protein

Gene ID

4204

Swiss Prot

P51608

Host

Rabbit

Cross Reactivity

Human

Target

MeCP2

Clonality

Polyclonal

Conjugation

Unconjugated

Source

Polyclonal antibody raised in rabbit against MeCP2 (Methyl-CpG-binding domain protein 2), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of the protein

Applications

WB, ELISA

Purification

Purified by Protein A.

Concentration

1.2µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

4204

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