WDR5 Polyclonal Antibody
Product Specifications
Background
Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
Synonyms
WD repeat-containing protein 5, WDR5, BMP2-induced 3-kb gene protein, BIG3
Gene ID
11091
Swiss Prot
P61964
Host
Rabbit
Cross Reactivity
Human
Target
WDR5
Clonality
Polyclonal
Conjugation
Unconjugated
Source
Polyclonal antibody raised in rabbit against human WDR5 (WD (tryptophan-aspartate) repeat domain 5), using a recombinant protein
Applications
WB
Purification
Protein G purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300
Concentration
2µg/µl
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
11091
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