CDYL Polyclonal Antibody

Product Specifications

Background

Acts as a RE1-silencing transcription factor (REST) corepressor that facilitates histone-lysine N-methyltransferase EHMT2 recruitment and H3K9 dimethylation at REST target genes for repression. Required for chromatin targeting and maximal enzymatic activity of polycomb repressive complex 2 (PRC2) ; acts as a positive regulator of PRC2 activity by bridging the pre-existing histone H3K27me3 and newly recruited PRC2 on neighboring nucleosomes. Has histone acetyltransferase activity, with a preference for histone H4.

Synonyms

CDYL1, Chromodomain Y-like protein, CDYL

Gene ID

9425

Swiss Prot

Q9Y232

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

CDYL

Clonality

Polyclonal

Conjugation

Unconjugated

Source

Polyclonal antibody raised in rabbit against human CDYL (chromodomain protein, Y-like) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein