ZBTB4 Polyclonal Antibody
Product Specifications
Background
Transcriptional repressor with bimodal DNA-binding specificity. Represses transcription in a methyl-CpG-dependent manner. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS) . Can also bind specifically to a single methyl-CpG pair and can bind hemimethylated DNA but with a lower affinity compared to methylated DNA (PubMed:16354688) . Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal.
Synonyms
Zinc finger and BTB domain-containing protein 4, ZBTB4
Gene ID
57659
Swiss Prot
Q9P1Z0
Host
Rabbit
Cross Reactivity
Human
Target
ZBTB4
Clonality
Polyclonal
Conjugation
Unconjugated
Source
Polyclonal antibody raised in rabbit against human ZBTB4 (zinc finger and BTB domain containing 4), using four different KLH-conjugated synthetic peptides
Applications
WB, ELISA
Purification
Whole antiserum from rabbit containing 0.05% azide
Concentration
Not Determined
Dilution
WB (1:300-5000), ELISA (1:500-1000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
57659
Curated Selection
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