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H3K4me2 Monoclonal Antibody

Product Specifications

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Gene ID

8350

Swiss Prot

P68431

Host

Mouse

Cross Reactivity

Human, Others

Target

H3K4me2

Clonality

Monoclonal

Isotype

IgG1

Clone

.

Conjugation

Unconjugated

Source

Monoclonal antibody raised in mouse against histone H3, dimethylated at lysine 4 (H3K4me2), using a KLH-conjugated synthetic peptide

Applications

WB, ELISA, IF

Purification

Purified by Protein G.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IF ()

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

8350

Cross Reactivity Details

A. Nidulansan

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