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CYP46 Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.

Synonyms

Cholesterol 24-hydroxylase; CP46; CYP46; CP46A_HUMAN; cytochrome P450 family 46.

Gene ID

10858

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

51-150/500

Target

CYP46

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human CYP46

Applications

WB, ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

10858

Predicted Cross Reactivity

Human, Rat, Dog, Cow, Sheep, Horse, Rabbit

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