Agpat2 Polyclonal Antibody, PE Conjugated
Product Specifications
Background
Agpat2 is a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. It is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in its have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Synonyms
LPAAB; BSCL; BSCL1; EC 2.3.1.51; LPAAB; LPAAT beta; Lysophosphatidic acid acyltransferase beta; 1 acyl sn glycerol 3 phosphate acyltransferase beta; 1 acylglycerol 3 phosphate O acyltransferase 2; 1 AGP acyltransferase 2; 1 AGPAT2 antibody Berardinelli Seip congenital lipodystrophy.PLCB_HUMAN
Gene ID
10555
Cellular Locus
Cell membrane
Host
Rabbit
Immunogen
121-220/278
Target
Agpat2
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human Agpat2
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
10555
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Horse
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