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HIV p55+NP7 Polyclonal Antibody, PE Conjugated

Product Specifications

Background

HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. p55 is digested by HIV1 protease into intermediate products p41 and p15. p41 is further digested into matrix protein p17 and capsid protein p24. Likewise, p15 is further digested into nucleocapsid protein p7 and to p6 and p1.

Synonyms

HIV1 Pr55Gag; Human immunodeficiency virus 1; Gag protein; Nucleocapsid protein p7

Host

Rabbit

Cross Reactivity

Virus

Immunogen

351-450/497

Target

HIV p55+NP7

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from HIV1 Nucleocapsid protein p7

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This antibody will recognize the full Gag protein and Nucleocapsid protein p7 after cleavage

Cross Reactivity Details

HIV

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