PIRH2 Polyclonal Antibody, AbBy Fluor™ 594 Conjugated
Product Specifications
Background
Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.
Synonyms
ZCHY; ARNIP; CHIMP; PIRH2; RNF199; ZNF363; PRO1996; RING finger and CHY zinc finger domain-containing protein 1; Androgen receptor N-terminal-interacting protein; CH-rich-interacting match with PLAG1; E3 ubiquitin-protein ligase Pirh2; RING finger protein 199; Zinc finger protein 363; p53-induced RING-H2 protein; hPirh2; RCHY1
Gene ID
25898
Swiss Prot
Q96PM5
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
31-130/261
Target
PIRH2
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 594
Source
KLH conjugated synthetic peptide derived from human PIRH2
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
590nm/617nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
25898
Predicted Cross Reactivity
Rat, Dog, Cow, Sheep, Pig, Horse
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7155909 Inquire
Rabbit anti-Saccharomyces cerevisiae (strain 204508/S288c)(Baker's yeast) IES1 Polyclonal Antibody
Ask
View Details 
123118-ML750 100 µL
AK1 (Adenylate Kinase Isoenzyme 1, AK 1, ATP-AMP Transphosphorylase 1, Myokinase) (MaxLight 750) discontinued
Ask
View Details 