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Hepatitis C Virus RNA-directed RNA polymerase Antibody, Biotin Conjugated

Product Specifications

Background

The RNA directed RNA polymerase is also known as non-structural protein NS5B. NS5B is a 65 kDa protein that resembles other viral RNA polymerases. Hepatitis C virus (HCV) replication is thought to occur in membrane bound replication complexes. These complexes transcribe the positive strand and the resulting minus strand is used as a template for the synthesis of genomic RNA. There are two viral proteins involved in the reaction, NS3 and NS5B

Synonyms

RNA-directed RNA polymerase; p68; RNA dependent RNA polymerase.

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Virus

Immunogen

2501-2600/3010

Target

Hepatitis C Virus RNA-directed RNA polymerase

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from Hepatitis C Virus RNA-directed RNA polymerase

Applications

WB, ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Cross Reactivity Details

HCV

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