Histone H4 (Acetyl K16) Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms

H4/p; Histone H4; HIST1H4A; H4/A; H4FA

Gene ID

121504

Swiss Prot

P62805

Modification Site

K17

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Mouse, Rat

Target

Histone H4 (Acetyl K16)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human Acetyl-Histone H4 (K17)

Applications

ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Acetylation

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

121504

Predicted Cross Reactivity

Human, Dog, Cow, Pig, Horse, Rabbit

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