Histone H4 (Acetyl K16) Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms
H4/p; Histone H4; HIST1H4A; H4/A; H4FA
Gene ID
121504
Swiss Prot
P62805
Modification Site
K17
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Mouse, Rat
Target
Histone H4 (Acetyl K16)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human Acetyl-Histone H4 (K17)
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Acetylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
121504
Predicted Cross Reactivity
Human, Dog, Cow, Pig, Horse, Rabbit
Curated Selection
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