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HOMER2 Polyclonal Antibody, PerCP Conjugated

Product Specifications

Background

Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses.

Synonyms

Cupidin; HOME2_HUMAN; HOMER 2; HOMER 2A; HOMER 2B; Homer homolog 2 Drosophila; Homer homolog 3; Homer neuronal immediate early gene 2; Homer protein homolog 2; Homer-2; Homer2; HOMER2A; HOMER2B; Vesl 2; Vesl2.

Gene ID

9455

Swiss Prot

Q9NSB8

Cellular Locus

Cytoplasm, Cell membrane, Extracellular matrix

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

301-354/354

Target

HOMER2

Clonality

Polyclonal

Isotype

IgG

Conjugation

PerCP

Source

KLH conjugated synthetic peptide derived from human HOMER2

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

482nm/677nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

9455

Predicted Cross Reactivity

Human, Cow, Pig, Rabbit

Curated Selection

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