TNFRSF10A Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
Synonyms
TR10A_HUMAN; Tumor necrosis factor receptor superfamily member 10A; APO2; DR4; TRAILR1; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1 (TRAIL receptor 1; TRAIL-R1) ; CD261
Gene ID
8797
Swiss Prot
O00220
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
34-239/468
Target
TNFRSF10A
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
Recombinant human DR4 protein
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8797
Curated Selection
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