Rogersonin E
Product Specifications
UNSPSC Description
Rogersonin E can be isolated from an Ophiocordyceps-associated fungus, Clonostachys rogersoniana. Rogersonin E downregulates the expression of PD-L1 protein in MDA-MB-231 and A549 cells[1].
Target Antigen
PD-1/PD-L1
Type
Natural Products
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rogersonin-e.html
Smiles
O=C(O[C@@H](C)CC[C@H](O)/C=C/1)CC2=C([C@H](C)OC1=O)N=C(N2C=N3)C4=C3N([C@@H]5O[C@H](CO)[C@@H](O)[C@H]5O)C=N4
Molecular Weight
531.52
References & Citations
[1]Hou X, et al. Rogersonins C-F, 9H-Imidazo[2,1-i]purine-Incorporating Adenine-Polyketide Hybrids from an Ophiocordyceps-Associated Clonostachys rogersoniana. J Nat Prod. 2024 Jun 28;87(6):1618-1627.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
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