Metiamide
Metiamide (SK&F 92058) is a histamine H2-receptor antagonist developed from another H2 antagonist, burimamide.
Product Specifications
CAS Number
[34839-70-8]
Product Name Alternative
SK&F 92058
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/Metiamide.html
Purity
97.84
Solubility
DMSO : 2.4 mg/mL (ultrasonic; warming) |H2O : 1.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
S=C(NCCSCC1=C(C)N=CN1)NC
Molecular Formula
C9H16N4S2
Molecular Weight
244.38
Precautions
H302, H315, H319, H335
References & Citations
[1]Alexandra Kikonyogo , Regina Pietruszko, Cimetidine and Other H2-Receptor Antagonists as Inhibitors of Human E3 Aldehyde Dehydrogenase. Molecular Pharmacology 1997; 52: 2267-271.|[2]Hendrik Preuss, Prasanta Ghorai1, Anja Kraus, Constitutive Activity and Ligand Selectivity of Human, Guinea Pig, Rat, and Canine Histamine H2 Receptors. JPET 2007 vol. 321no. 3 983-995.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H2 Receptor
Available Sizes
Curated Selection
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