ELAC2/HPC2 Polyclonal Antibody, Cy5 Conjugated
Product Specifications
Background
ELAC2 is a zinc phosphodiesterase which displays some tRNA 3' processing endonuclease activity. It is thought to be involved in tRNA maturation, acting by removing a 3' trailer from precursor tRNA. ELAC2 also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. A number of allelic variants have been investigated in hereditary prostate cancer.
Synonyms
ElaC homolog 2; ElaC homolog protein 2; ELC2; Heredity prostate cancer protein 2; HPC2; putative prostate cancer susceptibility protein HPC2/ELAC2; Ribonuclease Z2; RNase Z2; tRNA 3 endonuclease 2; tRNase Z long form; tRNase Z2; Zinc phosphodiesterase ELAC protein 2.
Gene ID
60528
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human
Immunogen
88-190/826
Target
ELAC2/HPC2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy5
Source
KLH conjugated synthetic peptide derived from human ELAC2
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
625,650nm/670nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
60528
Predicted Cross Reactivity
Mouse, Rat, Dog, Rabbit
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15345758 1 Vial
Lentiviral human OR6N2 shRNA (UAS) - Lentiviral human OR6N2 shRNA (UAS, RFP) (25)
Ask
View Details 
220701-01 50 µL
Alpha-SMA (ACTA2, AAT6, ACTSA, MYMY5, Actin, aortic Smooth Muscle, Alpha-Actin-2, Cell Growth-inhibiting Gene 46 Protein, alpha-SMA, a-SMA, aSMA, SMA-alpha, ) discontinued. see 554333
Ask
View Details 220701-02 100 µL
Alpha-SMA (ACTA2, AAT6, ACTSA, MYMY5, Actin, aortic Smooth Muscle, Alpha-Actin-2, Cell Growth-inhibiting Gene 46 Protein, alpha-SMA, a-SMA, aSMA, SMA-alpha, ) discontinued. see 554333
Ask
View Details 