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Jagged 2 Polyclonal Antibody, RBITC Conjugated

Product Specifications

Background

Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.

Synonyms

D12Ggc2e; HJ 2; HJ2; JAG 2; JAG2; Jagged 2 precursor; Jagged2; Syndactylism.

Gene ID

3714

Swiss Prot

Q9Y219

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

201-300/1238

Target

Jagged 2

Clonality

Polyclonal

Isotype

IgG

Conjugation

RBITC

Source

KLH conjugated synthetic peptide derived from human Jagged 2

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

1µg/µl

Dilution

WB (WB=1:500-2000), IF (IF=1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-4244R-RBITC

Specificity

There is a chance that this protein will cross-react with JAG1 based on 77% sequence similarity

Gene ID URL

3714

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Pig

Curated Selection

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